What is glutathione and why must we protect patient access to it? Understanding Glutathione Deficiency Invigor Medical Glutathione is such a critical soldier in our line of defense that our bodies make it themselves. We even have mechanisms that recycle and reuse it. But what happens when our toxic Glutathione depletion induces oxidative injury and apoptosis via TRPM2 channel activation in renal collecting duct cells ScienceDirect Glutathione Depletion and Stalwart Anticancer Activity of Metallotherapeutics Inducing Programmed Cell Death: Opening a New Window for Cancer Therapy ACS Omega