When people think about detox, they usually think about the liver. But detoxification actually involves several systems working together. One of the most important is methylation. Methylation supports processes involved in Transsulfuration Activity Can Support Cell Growth upon Extracellular Cysteine Limitation: Cell Metabolism Recent advances on gene related DNA methylation in cancer diagnosis, prognosis, and treatment: a clinical perspective Clinical Epigenetics Springer Nature Link PRMT1 mediated methylation of UBE2m promoting calcium oxalate crystal induced kidney injury by inhibiting fatty acid metabolism Cell Death & Disease Estrogen Metabolism, Detoxification, and Methylation Dr. Daniel Metzger, DACM, L.Ac.