The role of ROS in exercise mediated WAT browning. Exercise causes oxidative stress in skeletal muscle and reduces the level of GSH. GSH provides electrons for glutathione peroxidase (GPXs), which eliminates H2O2. Reducing Figure 1 from The Emerging Role of Glutathione in Alzheimer's Disease Semantic Scholar Figure 3 from Dossier : Oxidative stress pathologies and antioxidants The importance of glutathione in human disease Semantic Scholar The protection mechanism of proline from D galactosamine hepatitis involves the early activation of ROS eliminating pathway in the liver SpringerPlus Springer Nature Link Full article: Nanozyme mediated glutathione depletion for enhanced ROS based cancer therapies: a comprehensive review